AP214 ameliorates sepsis-induced acute kidney injury and mor(17)

NIH-PA Author Manuscript

NIH-PA Author Manuscript

NIH-PA Author ManuscriptFigure 7. NF-κB activation in kidney and spleen

NF-κB activation in kidney and spleen was evaluated by ELISA. AP214 was injected at 0 and6 hr (A, B) or only at 6 hr (delayed-treatment) (C, D). OD value of each sample was normalizedwith that of Raji cell nuclear extract. Values are mean ± SEM (n = 4 in sham-operated group,n = 6-7 in CLP group, n = 6-7 in AP214 group). #, P < 0.05 vs. CLP.