黄连的药理研究进展(5)

第29卷第2期　　　　　　　　　　　　　余园媛,等:　黄连的药理研究进展

[14]　郑凌云,周祖玉.黄连素对缺血再灌注心肌细胞损伤的

111

[21]　MITANIN,MURAKAMIK,YAMAURAT.InhibitoryEffect

ofBerberineontheMediastinalLymphNodeMetastasisProducedbyOrthotopicImplantationofLewisLungCarci2noma[J].CancerLetters,2001,165(11):359-427.

[22]　何贤辉,曾耀英,徐丽慧,等.黄连素对T淋巴细胞活化

保护作用[J].四川大学学报(医学版),2003,34(3):

452-454.

[15]　ZENGXH,ZENGXJ.EfficacyandSafetyofBerberine

forCongestiveHeartFailureSecondarytoIschemicorIdio2pathicDilatedCardiomoyopathy[J].TheAmericanIournalofCardiology,2003,92(7):173-176.

[16]　徐静华,于庆海,蔡爽,等.黄连解毒汤对小鼠急性脑缺

和增殖的抑制作用[J].中国病理生理杂志,2002,

18(10):1183-1186.

[23]　MANRINOVAEK,NIKOLOVADB,POPOVADN,et

al.SuppressionofExperimentalAntoimmuneTubulointer2stitialNephritisinBALB/CmicebyBerberine[J].nopharmacology,2000,48(12):9-16.

[24]　付晓春,王敏伟.黄连解毒汤的抗血栓作用研究[J].

Immu2

血、缺氧的影响[J].沈阳药科大学学报,2003,2(3):

132-134.

[17]　李运伦.黄连清降合剂对自发性高血压大鼠影响的实

验研究[J].山东中医杂志,2002,21(7):421-425.

[18]　李运伦.黄连清降合剂治疗原发性高血压46例临床研

沈阳药科大学学报,18(6):425-427.

[25]　张德付.3例[J].

究[J].中医杂志,2003,44(3):199-201.

[19]　王光平,唐发清.应用cDNA表达芯片研究复方黄连对

CNE1鼻咽癌移植瘤基因表达的影响[J].湖南医科大

,5)59.

[.学学报,2003,28(4):347-352.

[20]　KUOCL,CHICW.TheAnti2inflaof

BerberineinVitroandinV203(9):127-130.

[].中国民间疗法,2003,11(10):45-46.

[]张佳思,向国春.双黄连粉针剂在临床应用中配伍禁忌

的观察[J].中国局解手术学杂志,2001,10(4):

411-412.

AdvancesinPharmacologicalStudiesofCoptisChinesis

YUYuan2yuan,WANGBo2chu,PENGLiang,WANGJing2bo,ZENGChen

(KeyLaboratoryforBiomechanicsandTissueEngineeringUndertheStateMinistryofEducation,

CollegeofBioengineering,ChongqingUniversity,Chongqing400030,China)

Abstract:CoptisChinesisisthedryrhizomaofranunculaceousCoptisChinesisFranchorCoptisdeltoideaC.Y.Chenget

Hisao,orCoptisteetaWall.ItisthetraditionalChineseherb,whichisusedinthecontagiousdiseases.Inrecentyears,

itsnewpharmacologicalactionshavebeenreported,whichareantitumour,hypoglycemicresponse,immunoloregulation,improvingthefunctionsofcardiovascular.TheimportantpharmacologicalfunctionsofCoptisChinesisarehypoglycemicresponse,improvingthefunctionsofcardiovascular,antitumour.WiththedeeplyresearchingofCoptisChinesispharma2cology,andthecontinuousfoundingofpharmacologicalmechanism,newpreparationwillbewidelyappliedintheclinic.

Keywords:CoptisChinesis;antibacterial;antitumour;cardiovascularfunction;hypoglycemicresponse

(编辑　李胜春)